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The Alexander Hollaender Award in Biophysics is presented every three years and carries with it a $20,000 prize. The Award recognizes outstanding contributions made to the field of biophysics. Henrietta W. Hollaender established the Alexander Hollaender Award in Biophysics in honor of her husband, Alexander W. Hollaender, whom brought to prominence the field of photobiology. With an interest in the lethal and mutagenic effects of monochromatic ultra-violet radiation on cells, Dr. Hollaender identified the first clear indication that changes in nucleic acids needed to be analyzed, rather than proteins.
The Alexander Hollaender Award in Biophysics was first awarded in 1998 to Dr. Wayne A. Hendrickson for his contributions to macromolecular crystallography, specifically his development of robust methods of phasing and refinement, and determination of complex and biologically important structures. Dr. Hendrickson is best known for his work pioneering multi-wavelength anomalous diffraction (MAD) and its use as an analytical tool for protein crystallography.
King-Wai Yau, professor of neuroscience at the Johns Hopkins University School of Medicine, is the most recent recipient of the Alexander Hollaender Award in Biophysics. Yau is the major contributor of innovative and fundamental biophysical experiments and analyses that have transformed our understanding of how the signals from light and odor are recorded and relayed to the brain. As well as detailing specific, often surprising, molecular pathways and mechanisms, this has included identifying the non-image visual pigment systems responsible for light-entrainment of the circadian rhythm and explaining the factors that limit the possible wavelength range of vision in vertebrates.
King-Wai Yau (2013)
For innovative, rigorous, and fundamental contributions to the biophysics of sensory transduction in rod, cone, and non-image visual systems and in olfaction.
Watt W. Webb (2010)
For pioneering the applications of rigorous physical principles to the development of optical tools that have broadly impacted our ability to examine biological systems.
Barry H. Honig (2007)
For pioneering theoretical and computational studies of electrostatic interactions in biological macromolecules and of the energetics of protein folding.
Carlos J. Bustamante (2004)
For his ingenious use of atomic force microscopy and laser tweezers to study the biophysical properties of proteins, DNA, and RNA, one molecule at a time.
David J. DeRosier (2001)
For his development of three-dimensional image reconstruction methods, which have revolutionized electron microscopy of subcellular structures and his analytical visualization of cellular motility mechanisms.
Wayne A. Hendrickson (1998)
For his contributions to macromolecular crystallography, in the development of robust methods of phasing and refinement, and in determination of complex and biologically important structures.