Lynn M. Riddiford

University of Washington


Primary Section: 61, Animal, Nutritional, and Applied Microbial Sciences
Secondary Section: 22, Cellular and Developmental Biology
Membership Type:
Member (elected 2010)

Biosketch

B.A. in Biochemical Sciences, Radcliffe College (1958); Ph.D. in Zoology and Chemistry, Cornell University (1961); Research Fellow in Biology, Harvard University (1961-63; 1965-66). Instructor in Biology, Wellesley College (1963-65); Assistant (1966-71) and Associate Professor (1971-73) of Biology, Harvard University; Associate Professor (1973-5) and Professor (1975-2003) of Zoology and Virginia and Prentice Bloedel University Professor from 2000-2005, Professor of Biology (2003-7), emerita (2007-present), University of Washington. Senior Fellow, Janelia Research Campus, Howard Hughes Medical Institute (2007-2016).  Honors: NAS member; Fellow, American Academy of Arts and Sciences, AAAS, the Entomological Society of America (ESA), Royal Entomological Society, John S. Guggenheim Foundation (1979-80), Overseas Fellow, Churchill College, Cambridge University (2000-1). ESA Recognition Award in Insect Physiology, Biochemistry, and Toxicology (1997). G. J. Mendel Honorary Medal for Merit in the Biological Sciences (Czech Republic Academy of Sciences, 1998); Vollum Award for Distinguished Accomplishment in Science and Technology (Reed College, 2011); Washington State Academy of Sciences (2018); ICIPE@50 Achievement Award, ICIPE (2020). Chairman, Scientific Program Committee, Governing Council, International Center for Insect Physiology and Ecology (ICIPE), Nairobi, Kenya (1989-91); President, American Society of Zoologists (1991); President, Council for the International Congresses of Entomology (2000-4); President, Council of the International Federation of Comparative Endocrinological Societies (2001-5). 

Research Interests

My research over the years on molting and metamorphosis in the tobacco hornworm, Manduca sexta, was critical for its serving as a model for the endocrine regulation of post-embryonic development of insects.  One major theme has been to understand how juvenile hormone (JH) prevents the metamorphosis of a caterpillar to a moth and how it regulates embryogenesis.  We also have contributed to the application of JH as an Insect Growth Regulator (IGR) currently used in mosquito and flea control and some integrated pest management schemes for agricultural lepidopteran pests.  Hormones and behavior in Lepidoptera and sex pheromone reception were other early themes in my research. At Janelia, I studied the hormonal regulation of neurodevelopment and behavior in Drosophila.  Presently, at Friday Harbor Laboratories, I am continuing to study the role of JH in metamorphosis of the Drosophila nervous system and studying the regulation of metamorphosis in Crustacea.  Jim Truman and I are continuing our collaboration on the evolution of metamorphosis. We are particularly interested in how the hormonal control of embryonic development in ancestral insects may have driven the evolution of complete metamorphosis. Currently, we are studying the effects of JH on embryonic and early nymphal development of silverfish.

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