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Nanomaterials in Biology and Medicine: Promises and Perils
Organized by Robert Austin, this meeting was held on April 10-11, 2007 at the National Academy of Sciences in Washington, D.C. Audio recordings and slides from the presentations are being made available as they are approved.
Meeting Overview There has been an explosive development in materials development which uses nanoscale materials to probe biological processes and diagnose medical conditions (such as tumor detection). There are unique aspects of nanoscale materials which allow them to preferentially penetrate and be retained by biological cells and tissue and there have been developments in new ways to detect and image and nanomaterials in cells and biological tissue. Further, the size scale of nanoprobes will allow us to build complexity into nanoprobes which allow them to be multi-functional, with both diagnostic and drug delivery. However, we must also be aware that these nanomaterials can have drastically different behavior in biological tissue than larger scale materials of exactly the same composition, so issues of societal and ethical outcomes must also be considered.
To view presentations, click on title. Click on speaker name to link to speaker lab or home page.
Session 1: New technologies to create functional nanomaterials Opening Remarks - Robert Austin (Princeton University)
Shuang-Fang Lim (Princeton University) Nano-upconversion phosphors
Chad Mirkin (Northwestern University) Nanotechnological approaches to amplification in chemical and biological systems
Charles Lieber (Harvard University) Designed Nano-biosensors
Angela Belcher (Massachusetts Institute of Technology) Evolution of biometic nanomaterials
Session 2: Societal and ethical concerns of nanotechnology in biology
Jeffery Schloss (The National Human Genome Research Institute) Genomic information for individuals opportunities and challenges for nanotechnology
Oleg Salata (Oxford University) Nanoparticles known and unknown health risks
Vikki Colvin (Rice University) Sustainability for nanotechnology
K. Eric Drexler (Nanorex, Inc.) The road to advanced nanotechnologies: health issues and applications
Sackler Lecture George Whitesides (Harvard University) Nanoscience and Nanotechnology: A Portrait in Early Adolescence
Session 3: Functional nanomaterials in biology Lisa Brannon-Peppas (University of Texas, Austin) Targeted Delivery of Nanoparticulate Drug Delivery Systems
Uwe B. Sleytr (University of Natural Resources and Applied Life Sciences, Vienna) A molecular construction kit for nanobiotechnological applications
Barbara Baird (Cornell University) Engineered Materials to Investigate Spatial Control of Cellular Signaling
Herc Neves (BioMEMS, IMEC, Belgium) Micro/Nanosystem integration in healthcare
Robert Prod’homme (Princeton University) How size matters in the retention of nanomaterials in tissue
Session 4: Frontiers of nanotechnology
Nadrian Seeman (New York University) DNA: not merely the secret of life
Olgica Bakajin (Lawrence Livermore National Laboratory) Bio-Inspired and biocompatible carbon nanotube Materials
Steve Chou (Princeton University) 10nm large area patterning for bio sending and analysis
Closing Remarks Robert Austin (Princeton University)
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