Rodolphe Barrangou

North Carolina State University


Election Year: 2018
Primary Section: 26, Genetics
Secondary Section: 62, Plant, Soil, and Microbial Sciences
Membership Type: Member

Biosketch

Rodolphe Barrangou is a microbiologist recognized for his work on food bacteria and their roles and uses as starter cultures and probiotics. He is known particularly for establishing CRISPR as the bacterial adaptive immune system which provides resistance against bacteriophages, the characterization of the CRISPR-Cas system mechanism of action, and their use in various food applications. Barrangou was born in France, grew up in Paris, and emigrated to the US in 1998 to pursue a MS and then a PhD at NC State University. He worked in the industry for nearly a decade before returning to academia, and has also been involved in several start-up companies commercializing various applications and products based on CRISPR technologies. He is a member of the National Academy of Sciences.

Research Interests

Barrangou is focusing on the characterization of CRISPR-Cas systems, and their applications in bacteria. The CRISPRlab has published numerous studies on the various applications of CRISPR-Cas systems, and illustrated their use for the study and development of probiotics, including for genotyping, phage resistance, and genome editing to understand and enhance health-promoting functions of interest. The work has spanned basic scientific to understand and decipher the genomics of lactic acid bacteria, as well as developing novel technologies and applying them to develop and formulate next-generation probiotic strains.

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