Mortimer Mishkin

National Institutes of Health


Election Year: 1984
Primary Section: 28, Systems Neuroscience
Secondary Section: 52, Psychological and Cognitive Sciences
Membership Type: Member

Research Interests

A multidisciplinary approach is used to study the neurobiological mechanisms underlying learning and memory in monkeys. The approach involves: (1) studying the effects of selective cerebral lesions in monkeys trained on specially designed behavioral learning and cognitive memory tasks, in the attempt to separate and identify different mnemonic functions and localize their critical neural substrates in the basal ganglia and limbic system; (2) applying anatomical tracing techniques, to reveal how the different substrates belonging to a functional family are organized as components of a neural system or circuit; (3) recording electrophysiological activity within the identified substrates, to determine the nature of the information those neurons receive and transmit before, during, and after learning; and (4) injecting pharmacological agents into those same substrates to begin the work of relating the learning-dependent changes in behavior and neuronal activity to the underlying cellular and synaptic mechanisms.

Powered by Blackbaud
nonprofit software