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Tissue engineering is an interdisciplinary field that marries the principles of engineering and the life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function. Typically, tissue engineers use advanced biomaterials that serve as scaffolds for the delivery of cells, and the scaffolds further provide cues and signals to the cells to guide their re-growth or healing of a tissue. This talk will include specific examples to illustrate the complexities of designing tissue engineering strategies for clinical use, such as regenerating damaged cartilage, engineering living heart valves, or treating Parkinson’s disease. Finally, all of this will be placed in the context of the many scientific and regulatory challenges that exist and provide insight related to the future promise of this field in medicine.
Kristi Anseth (NAS), University of Colorado Boulder
This lecture is co-sponsored by the OC Chapter of Archeological Institute of America. This talk will frame recent VEP modeling and empirical research on the central Mesa Verde and northern Rio Grande regions within a much larger picture of population growth reconstructed from osteological remains and movement reconstructed from tree-ring dates for the entire upland Southwest.
Tim Kohler is Regents' Professor of Anthropology at Washington State University
Groundwater is a critical source of drinking water for many Americans, it is the drought insurance for 40% of our planet's agriculture, and it sustains many aquatic ecosystems. Understanding this hidden resource is a key to it's sustainable management.
Thomas Harter, PhD, is the Robert M. Hagan Endowed Chair in Water Management and Policy at the University of California, Davis.
There is an urgent need to translate genome-era discoveries into clinical utility, but the difficulties in making bench-to-bedside translations may be helped by the nascent field of translational bioinformatics. Dr. Butte's lab at Stanford builds and applies tools that convert trillions points of molecular, clinical, and epidemiological data -- measured by researchers and clinicians over the past decade and now commonly termed “big data” -- into diagnostics, therapeutics, and new insights into disease. This talk will highlight how publicly-available molecular measurements to find new uses for drugs including drug repositioning for inflammatory bowel disease, discovering new treatable inflammatory mechanisms of disease in type 2 diabetes, and how the next generation of biotech companies might even start in your garage.
Atul Butte, Stanford University School of Medicine
After decades of planning and a 9-year journey, the New Horizons spacecraft will reach Pluto on July 14, 2015, providing our first close-up view of the Kuiper Belt Object and its five moons.
Fran Bagenal, Professor of Astrophysical and Planetary Sciences
Laboratory for Atmospheric and Space Physics, University of Colorado
Cancer Immunoediting is the process by which the immune system controls and shapes cancer. In its most complex form, cancer immunoediting occurs in three phases: Elimination (the host protective phase of the process), Equilibrium (where tumor cells that survive immune elimination are maintained in a state of functional tumor dormancy) and Escape (where clinically apparent tumors emerge because immune sculpting of the tumor cells has produced variants that display either reduced immunogenicity or enhanced immunosuppressive activity).
Robert Schreiber (NAS), Washington University School of Medicine