Genetic Engineering of Viruses and Viral Vectors
Organized by Peter Palese and Bernard Roizman
June 9-11, 1996
Irvine, CA
Sunday, June 9
Session One
Elliott Keiff, Chair
Welcome
Site-Specific Integration by Adeno-Associated Virus
Kenneth I. Berns, Cornell University
Biology of Adenovirus Vectors
Thomas E. Shenk, Princeton University
A New Adenoviral Vector of High Capacity and Lacking Adenoviral Gene Expression
C. Thomas Caskey, Merck
Gene Therapy for Metastatic Disorders with Recombinant Viral Vectors
Savio L.C. Woo, Baylor College of Medicine
Session Two
Kenneth I. Berns, Chair
Gene Content and Genetic Engineering of Herpes Simplex Viruses
Bernard Roizman, University of Chicago
The Application of Genetically Engineered Herpes Simplex Virus for the Treatment of Brain Tumors
Richard J. Whitley, University of Alabama
Replication-Defective HSV Vectors for Gene Transfer In Vivo
Joseph C. Glorioso, University of Pittsburgh
Expression of Latent Cytomegalovirus Genes in Hematopoietic Progenitors
Edward S. Mocarski, Stanford University
Research Effects of Human Cytomegalovirus Early Glycoprotein on MHC Class I Heavy Chains
Thomas R. Jones, Wyeth-Ayerst
Monday, June 10
Session Three
Inder M. Verma, Chair
Genetic Engineering of Influenza Viruses
Peter Palese, Mount Sinai School of Medicine
Assembly of New Envelopes on VSV Vectors
John K. Rose, Yale University
Infection of Target Cells by Rhabdovirus Vectors Possessing Heterologous Spike Glycoproteins
Karl-Klaus Conzelmann, Federal Research Center for Virus Diseases of Animals, Tubingen
Alpha Virus-Based Expression Vectors: Strategies and Applications
Charles M. Rice, Washington University
Early Events in Poliovirus Infection: Virus-Receptor Interactions
Vincent R, Racaniello, Columbia University
Session Four
Thomas E. Shenk, Chair
Retroviral Vectors: Targeting and Transduction of Non-Dividing Cells
Inder M. Verma, Salk Institute
Genetic Manipulation of the Nef Locus of SIV and HIV
Ronald C. Desrosiers, Harvard Medical School
Development of HIV Vectors for HIV Gene Therapy
Flossie Wong-Staal, University of California, San Diego
Evolution and Application of Retroviral Vectors
Richard C. Mulligan, Whitehead Institute of Biochemical Research
Cell-Surface Receptors for Retroviruses and Implications for Gene Transfer
A. Dusty Miller, Fred Hutchinson Cancer Center
Tuesday, June 11
Session Five
Bernard Moss, Chair
EBV Genomes Capable of Maintaining 100kbp of Foreign DNA as Episomes in Immortal Cell Lines
Elliott Kieff, Harvard Medical School
Genetically Engineered Poxviruses and Their Uses for Gene Expression and Vaccination
Bernard Moss, National Institutes of Health
Application of Poxvirus Vectors to Vaccination: An Update
Enzo Paoletti, Virogenetics
DNA Vaccines: Plasmid DNA as a Delivery System
Margaret A. Liu, Merck
Fusigenic Viral-Liposome for Gene Therapy in Cardiovascular Disease
Victor J. Dzau, Stanford University
Concluding Remarks
Support From The Following Companies is Gratefully Acknowledged:
Aviron
Bristol-Meyers Squibb
Merck
Pasteur-Merieux
