Links Between Recombination and Replication: Vital Roles of Recombination
Organized by Charles Radding
November 10-12, 2000
Irvine, CA
A Colloquium sponsored by the National Academy of Sciences
Recombination and an overview of the links between recombination and replication
A. John Clark, Chair
An overview of recombinational repair in prokaryotes
Michael Cox, University of Wisconsin-Madison
RecBCD and its role in intiation of recombination
Stephen Kowalczykowski, University of California, Davis
The nucleoprotein filament
Takehiko Shibata, Riken Institute
D-loops, paranemic joints, and the recognition of homology
Charles Radding, Yale University
Structure of RecA, Rad51 and RadA Filaments and Rings
Edward Egleman, University of Virgina
Enzymology of Recombination in S. cerevisiae
Patrick Sung, University of Texas Health Science Center at San Antonio
Homologous recombination in S. pombe
Gerald Smith, Fred Hutchinson Cancer Research Center
Homologous recombination and Non-homologous end joining
Stephen West, Clare Hall Laboratories
Intron mobility with or without recombination
Marlene Belfort, University of Albany
Session II: Double-strand break repair
Tomoko Ogawa, Chair
MRE11 and double-strand break repair
Tomoko Ogawa, Osaka University
MRE11 and the cellular response to DNA damage
John Petrini, University of Wisconsin
Enzymology of double-strand break repair
Martin Gellert, National Institutes of Health
DNA PK and Ku
Stephen Jackson, Wellcome/CRC Institute
Regulation of double-strand break hotspots in S. cerevisiae
Alain Nicolas, Institut Curie
Repair of DNA damage and cell-cycle checkpoints
Rodney Rothstein, Columbia University
Genetics of homologous recombination in mammalian cells
Shunichi Takeda, Kyoto University
Roles of ATM homologs for DNA metabolism
Nancy Kleckner, Harvard University
Day 2:
Session III: An overview of replication
Bruce Alberts, Chair
Enzymology of Replication in E. coli
Michael O'Donnell, Rockefeller University
Kinetic studies of replication
Steven Benkovic, Pennsylvania State University
Processivity of mammalian DNA polymerases
Jerard Hurwitz, Sloan-Kettering Cancer Center
Initiation of replication in yeast
Stephen P. Bell, Massachusetts Institute of Technology
Intermediates in replication
Nicholas Cozzarelli, University of California, Berkeley
EM Analysis of replication forks at a pyrimidine dimer
Jack D. Griffith, University of North Carolina
SOS mutagenesis
Myron Goodman, University of Southern California
Damage bypass by DNA polymerase eta
Satya Prakash, University of Texas
Session IV: Recombination, replication and mutagenesis
Gisela Mosig, Chair
Mutagenesis associated with initiation of Phage T4 replication
Gisela Mosig, Vanderbilt University
The T4 recombination filament
Scott Morrical, University of Vermont College of Medicine
Coupling of replication and recombination of Phage T4
Kenneth Kreuzer, Duke University
Multiple functions of PriA
Steven Sandler, University of Massachusetts
Origin-independent initiaion at D-loops in vitro
Kenneth Marians, Sloan-Kettering Cancer Center
Role of PriA in forming replication forks
Hiroshi Nakai, Georgetown University Medical Center
Session V: Current views of copy-choice recombination
James Haber,Chair
Chromosome instability
Richard D. Kolodner, University of California, San Diego
The interaction of DNA replication, repair and recombination in trinucleotide repeat instability
David Leach, University of Edinburgh
Multiple recombination pathways in S. cerevisiae
James Haber, Brandeis University
Break-join and copy-choice pathyways in E. coli
Susan Rosenberg, Baylor College of Medicine
RadC in double-strand break repair
Susan Lovett, Brandeis University
Recombination and replication in mammalian cells
Maria Jasin, Sloan-Kettering Institute
Session VI: Rescue of replication forks and segregation of recombined chromosomes
Robert Lloyd,Chair
Vital Role for recombination in processing aberrant replicaiton intermediates and at-risk motifs
Michael Resnick, NIEHS, NIH
RNA polymerase and rescue of replication forks
Robert Lloyd, University of Nottingham
Genetics of replication fork rescue in E. coli
B. Michel
Genetics of replication fork rescue
Philip Hanawalt, Stanford University
Resolution of dimeric chromosome produced by recombination
David Sherrat, University of Oxford
Resolution of Holliday structures vs. chromosome partition
Hideo Shinagawa, Osaka University
On the rescue of ruptured replication forks
Andrei Kuzminov, University of Oregon
