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Nanomaterials in Biology and Medicine: Promises and Perils

Organized by Robert Austin

April 10-11, 2007
Washington, DC

Meeting Overview:
There has been an explosive development in materials development which uses nanoscale materials to probe biological processes and diagnose medical conditions (such as tumor detection). There are unique aspects of nanoscale materials which allow them to preferentially penetrate and be retained by biological cells and tissue and there have been developments in new ways to detect and image and nanomaterials in cells and biological tissue. Further, the size scale of nanoprobes will allow us to build complexity into nanoprobes which allow them to be multi-functional, with both diagnostic and drug delivery. However, we must also be aware that these nanomaterials can have drastically different behavior in biological tissue than larger scale materials of exactly the same composition, so issues of societal and ethical outcomes must also be considered.

Video Available

Session I: New technologies to create functional nanomaterials

Robert Austin, Princeton University
Opening Remarks

 Nano-upconversion phosphors
Shuang-Fang Lim, Princeton University

Nanotechnological approaches to amplification in chemical and biological systems
Chad Mirkin, Northwestern University

 Designed Nano-biosensors
Charles Lieber, Harvard University

Evolution of biometic nanomaterials
Angela Belcher, Massachusetts Institute of Technology

Session II: Societal and ethical concerns of nanotechnology in biology

 Genomic information for individuals opportunities and challenges for nanotechnology
Jeffery Schloss, The National Human Genome Research Institute

 Nanoparticles known and unknown health risks
Oleg Salata, Oxford University

 Sustainability for nanotechnology
Vikki Colvin, Rice University

 The road to advanced nanotechnologies: health issues and applications
K. Eric Drexler, Nanorex, Inc.

Sackler Lecture
 Nanoscience and Nanotechnology: A Portrait in Early Adolescence
George Whitesides, Harvard University

Session III: Functional nanomaterials in biology

 Targeted Delivery of Nanoparticulate Drug Delivery Systems
Lisa Brannon-Peppas, University of Texas, Austin

 A molecular construction kit for nanobiotechnological applications
Uwe B. Sleytr, University of Natural Resources and Applied Life Sciences, Vienna

 Engineered Materials to Investigate Spatial Control of Cellular Signaling
Barbara Baird, Cornell University

 Micro/Nanosystem integration in healthcare
Herc Neves, BioMEMS, IMEC, Belgium

 How size matters in the retention of nanomaterials in tissue
Robert Prod’homme, Princeton University

Session IV: Frontiers of nanotechnology

 DNA: not merely the secret of life
Nadrian Seeman, New York University

Bio-Inspired and biocompatible carbon nanotube Materials
Olgica Bakajin, Lawrence Livermore National Laboratory

 10nm large area patterning for bio sending and analysis
Steve Chou, Princeton University

Robert Austin, Princeton University
Closing Remarks


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