Research Interests
My interest is in developing new therapies for cancer by making fusion proteins composed of the Fv portion of antibodies directed at antigens on cancer cells fused to a genetically modified form of a powerful bacterial toxin, Pseudomonas exotoxin A. These chimeric proteins which are termed recombinant immunotoxins are being tested in humans with various forms of cancer. I also study the human multidrug resistance gene, MDR1, and how this resistance gene can be used in gene therapy.
Membership Type
Member
Election Year
1982
Primary Section
Section 41: Medical Genetics, Hematology, and Oncology
Secondary Section
Section 42: Medical Physiology and Metabolism