John R. Roth

My research revolves around genetic analysis of bacteria and genetic approaches to bacterial metabolism and its regulation in these systems, specifically, histidine and purine synthesis, proline degradation, NAD synthesis and recycling, vitamin B12 synthesis, and ethanolamine utilization; chromosome rearrangements (duplications and inversions) and the recombination mechanisms by which they form; evolution of the bacteria genome; and transposons and their application to bacterial genetics.