Allison, James 2018 Jessie Stevenson Kovalenko Medal

Allison, James 2018 Jessie Stevenson Kovalenko Medal

Join us in congratulating James P. Allison!

James P. Allison, The University of Texas MD Anderson Cancer Center, received the 2018 Jessie Stevenson Kovalenko Medal.

Allison’s pioneering research has had a vast impact on cancer therapy and the evolution of the entire field of cancer immunology. His work has advanced science while improving the health and wellbeing of cancer patients worldwide, a process that continues to this day.

This path began in 1983 when Allison reported on the protein structure of T cell receptor, providing one of the earliest looks at the molecules involved in T cell function. This led to the discovery of two molecules related to the activation of T cells, CD28 and CTLA-4, the second of which functions as an inhibitor that restricts T cell responses. In 1996 Allison showed that blocking CTLA-4 led to tumor rejection in mice. This opened up the field of “immune checkpoint therapy,” a paradigm shift in cancer treatment which targeted the immune system rather than tumors themselves.

After several years of clinical trials, CTLA-4 was approved as a standard treatment for patients with metastatic melanoma. It is currently being tested in several additional forms of tumors and has already benefitted the lives of tens of thousands of patients.

The Jessie Stevenson Kovalenko Medal is awarded every two years for outstanding research in the medical sciences. The award is presented with a medal, a $25,000 prize and $50,000 to support the recipient's research.

Please use the following sample social media posts and other materials to congratulate James P. Allison.

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 Watch James P. Allison of @MDAndersonNews receive @theNASciences Jessie Stevenson Kovalenko Medal at #NAS155 on April 29! He is receiving the Kovalenko Medal for important medical discoveries related to the body’s immune response to tumors. The award in medical sciences will be presented during the 155th NAS Annual Meeting on Sunday, April 29.

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Congratulations James P. Allison of @MDAndersonNews, recipient of @theNASciences Jessie Stevenson Kovalenko Medal! #CancerTherapy #EndCancer #NASmember

 James P. Allison of @MDAndersonNews earns 2018 @theNASciences Jessie Stevenson Kovalenko Medal for his impact on cancer therapy and cancer immunology!

Watch James P. Allison of @MDAndersonNews receive @theNASciences Jessie Stevenson Kovalenko Medal at #NAS155 on April 29! #CancerTherapy

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Watch Allison's Acceptance Speech »

Press Release »

Jessie Stevenson Kovalenko Medal »

2018 NAS Award Recipients »

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